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There are two main types of mutations: point mutation and…

There are two main types of mutations: point mutation and frameshift mutations. In each of the following DNA sequences, you will use the mRNA and amino acid sequences to identify the mutation that occurred and the effects of each, if any. Look and analyze carefully.

 

Question 1

Original DNA Sequence: T A C A C C T T G G C G A C G A C T

mRNA Sequence: AUG UGG ACC CGC UGC UGA 

Amino Acid Sequence: Met-Thr-Asn-Arg-Cys-stop

 

Question 2

Mutated DNA Sequence #1: A C A T C T T G G C G A C GA C T

What’s the mRNA sequence? (Indicate the change) UGU-AGA-ACC-GCU-GCU-GA

What will be the amino acid sequence? Cys-Arg-Thr-Ala-Ala

Will there likely be effects?______________________

What kind of mutation is this?______________________

Question 3

Mutated DNA Sequence#2: T A C G A C C T T G G C G A C G A C T

What’s the mRNA sequence? (Indicate the change) AUG-CUG-GAA-CCG-CUG-A

What will be the amino acid sequence? Met-Leu-Glu-Pro-Leu-

Will there likely be effects? _______________________________________________

What kind of mutation is this? ____________________________________________

Question 4

Mutated DNA Sequence#3: T A C A C C T T G G C G A C T A C T

What’s the mRNA sequence? (Indicate the change) AGU-UGG-AAC-CGC-UGA-UGA

What will be the amino acid sequence? Met-Trp-Asn-Arg-stop-stop

Will there likely be effects? _______________________________________________

What kind of mutation is this? ____________________________________________

Question 5

Mutated DNA Sequence #4: T A C A C C T T G G G A C G A C T

What kind of mutation is this? ____________________________________________

What will be the corresponding mRNA sequence? AUG-UGG-AAC-CCU-GCU-GA

What will be the amino acid sequence? Met-Trp-Asn-Pro-Ala-

Will there likely be effects? _______________________________________________

What kind of mutation is this? ____________________________________________

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