There are two main types of mutations: point mutation and frameshift mutations. In each of the following DNA sequences, you will use the mRNA and amino acid sequences to identify the mutation that occurred and the effects of each, if any. Look and analyze carefully.
Question 1
Original DNA Sequence: T A C A C C T T G G C G A C G A C T
mRNA Sequence: ___________________________________________
Amino Acid Sequence: _________________________________________
Question 2
Mutated DNA Sequence #1: A C A T C T T G G C G A C GA C T
What’s the mRNA sequence? (Indicate the change) ____________
What will be the amino acid sequence?____________________
Will there likely be effects?______________________
What kind of mutation is this?______________________
Question 3
Mutated DNA Sequence#2: T A C G A C C T T G G C G A C G A C T
What’s the mRNA sequence? (Indicate the change) ________________________
What will be the amino acid sequence? ____________________________________
Will there likely be effects? _______________________________________________
What kind of mutation is this? ____________________________________________
Question 4
Mutated DNA Sequence#3: T A C A C C T T G G C G A C T A C T
What’s the mRNA sequence? (Indicate the change) _________________________
What will be the amino acid sequence? ____________________________________
Will there likely be effects? _______________________________________________
What kind of mutation is this? ____________________________________________
Question 5
Mutated DNA Sequence #4: T A C A C C T T G G G A C G A C T
What kind of mutation is this? ____________________________________________
What will be the corresponding mRNA sequence? __________________________
What will be the amino acid sequence? ____________________________________
Will there likely be effects? _______________________________________________
What kind of mutation is this? ____________________________________________
Question 6
What is the relationship between DNA, codons, and proteins?
Question 7
How does the shape of a protein relate to its function?
Question 8
Why are frameshift mutations likely to cause more problems than point mutation?